Holoflux

Exploratory projects

Exploratory projects

Projects arranged by date in the table.
Arranged alphabetically by acronym, below.

Date

Acronym

Project title

Coordinators

2023-2024

MOtheRS

Monitoring the gut microbiota, resistance against salmonella, the animal performance and immune response through an adult pathogen-free flora

Florent KEMPF

2022-2023

INT-BXL

Introgression of the biodegradation capacities of xenobiotics in polluted soils and sediments

Aymé SPOR, Stéphane PESCE

2022-2023

MOMIE

Modulation of the oral microbiota by the technological microbiota of a fermented food

Eric NEYRAUD, Philippe GERARD

2021

EggToMeat

Proof of concept and construction of a project to identify the impact of farming parameters on bacterial flux in the production of broilers

Monique ZAGOREC

2020-2021

EnterotyPig

Gut microbiota enterotypes in pigs: detailed characterisation and influence of host genetics on holobiont assembly

Claire ROGEL-GAILLARD

2020-2021

HOLOBROM

Maternal effects and environmental filtering of microbial fluxes from parent plants to their offspring

Céline LEROY
Heidy SCHIMANN

2020-2021

Holopig

Unraveling the role of gut microbiota-derived metabolites in neonatal programming of intestinal epithelial cells by primocolonizing bacteria in piglets

Martin BEAUMONT
Gaëlle BOUDRY

2020-2021

HOUSE

The plant-microbiota holobiont in the rhizosphere: a selection unit?

Manuel BLOUIN

2020-2021

µFlyAdapt

Role of plant-microbiota interactions in the adaptation of a pest insect to its host

Christophe MOUGEL

2020-2021

MicroWean

Altered vertical microbiota transmission due to early weaning and its effects on host health

Rebeca MARTIN ROSIQUE

In this folder

Chicks INRAE
The EggToMeat project aims at identifying the impact of farming parameters on the flux of microbiota along the chicken production chain, from eggs to carcasses. For that purpose, two housing conditions (indoors vs outdoor range) will be compared on a single batch of embryonated eggs.
© INRAE
The EnterotyPig project is part of area 1 of the metaprogramme which focuses on studying the assembly and interaction mechanisms within holobionts in farmed livestock, in this case pigs. This project concerns analysis of the genetic determinism of the host in the construction of the holobiont and its evolution over life, and a differential functional analysis of two enterotypes (i.e. types of microbiota) found to be dominant under our rearing conditions.
© Comscience
The HOLOBROM project study the acquisition and transmission of microbial endophytes (i.e. living inside a plant) in the development and growth of plants. Works on cultivated species have suggested maternal effects, but they remain relatively unknown in natural ecosystems which are subject to marked environmental gradients.
Marek Piwnicki - Unsplash
The HOLOPIG project concerns the microbial control of the maturation of the intestinal epithelial barrier and its long-term effects on health in mammals, We propose using the pig holobiont as a model to identify the mode of action of primocolonising bacteria on host epithelial cells.
© INRAE LIPME
The HOUSE project will try to answer evolutionary science questions by mobilising microbial ecology and plant biology methods. It aims to analyse the pertinence of the holobiont concept using artificial selection of the plant, the rhizosphere microbiota, or both at the same time, in order to determine the importance of plant-microbiota interactions in the response to selection.
© INRAE
The INT-BXL project deals with the bioremediation of polluted river sediments and agricultural soils. In agroecosystems, the contamination of soils by xenobiotic compounds, such as pesticides used in conventional agriculture and antibiotics used to treat livestock or supplied via organic soil fertilisation, can lead to the transfer of these compounds, and/or their degradation intermediaries, towards surface and ground water, thus contaminating all water resources.
Photo d'une mouche
The µFlyAdapt project aims to highlight the selective recruitment and role of rhizosphere microorganisms in the adaptation of a phytophagous root insect (the cabbage maggot Delia radicum) to its host plant (Brassica napus).
© INRAE
The MicroWean project focuses on the microbial colonisation of mucosal surfaces during the early days of life, a process that is essential to neonatal development.
© INRAE
The MOMIE project concerns the study of the influence of a fermented diet on the microbiota of the mouth and on taste perception. The model used is the rat, but the aim is to extrapolate this work to the human holobiont.
© CDC - Unsplash
The MOTHERS project concerns the control of the gut microbiota in chickens. It aims to inoculate a previously selected microbiota, free of pathogens, to allow the installation of an intestinal microbiota with beneficial effects on the immune response, a barrier effect against salmonella and the improvement of the zootechnical performance of poultry.

Modification date : 27 October 2023 | Publication date : 08 November 2021 | Redactor : Com, DC